The populations of the towns that League 2 clubs play in are mostly far higher than those containing Highland, Lowland and Junior teams, with only a few exceptions, e.g Irvine Meadow/Vics, Linlithgow, Kilwinning, Kirkintilloch. If you asked most fans of League 2 clubs their thoughts on playing in a regionalised league they would see it as less prestigious and a backwards step, regardless of any potential financial benefit. In fact I doubt any studies have ever been done to explore the benefits and drawbacks of such a reorganization.